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Hair Dye

p- Phenylene-diamine and its salts

CAS 106-50-3 / 624-18-0 / 16245-77-5
20

Safety score · 0–100

Caution

Derived from EU CosIng regulatory status, PubChem hazard data and published research. How we score.

PPD — the workhorse permanent hair-dye intermediate. EU caps it at 2% in hair dye with a sensitisation warning; one of the leading causes of hair-dye allergic dermatitis.

Skin benefits

  • Permanent oxidative hair-dye precursor
  • Wide shade range

Known concerns

  • EU Annex III restricted (max 2% in hair dye, must carry warning)
  • Strong skin sensitiser — frequent ACD culprit
  • Banned in eyelash/eyebrow dyes
  • Acute toxicity if ingested

References

EU

EU CosIng database

European Commission cosmetic ingredient registry: regulatory status, restrictions, authorised functions.

Related hair dyes

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This profile is for educational purposes and does not constitute medical advice. Regulatory status and scientific understanding evolve, so always read the physical product label and consult a healthcare professional for personal concerns.