P-METHOXYCINNAMALDEHYDE
Other
Moderate
CAS Number: 1963-36-6
About P-METHOXYCINNAMALDEHYDE
P-Methoxycinnamaldehyde is a cosmetic ingredient used in product formulations. Its specific function may vary between products. Exercise caution due to limited available safety data.
Detailed Analysis
p-Methoxycinnamaldehyde is an aromatic aldehyde with a methoxy substituent on the benzene ring and an alpha,beta-unsaturated carbonyl system responsible for its distinctive spicy-sweet fragrance. The cinnamaldehyde scaffold is known to cause skin sensitization in susceptible individuals, though the methoxy substitution may moderate this effect. EU Regulation 1223/2009 requires allergen labeling for this compound when present above 0.001% in leave-on products. The compound demonstrates some antioxidant activity but is primarily valued for its fragrance contribution. The alpha,beta-unsaturated nature raises theoretical concerns about Michael addition reactivity with skin proteins, contributing to its sensitizing potential.
Skin Benefits
- ✓ Fragrance ingredient with pleasant aromatic profile
- ✓ May provide mild antioxidant activity
Known Concerns
- ⚠ Skin sensitization potential (alpha,beta-unsaturated aldehyde)
- ⚠ EU allergen labeling required above threshold
- ⚠ Potential for protein reactivity via Michael addition
- ⚠ May cause irritation in sensitive individuals
Safety Score
Moderate
Based on EU regulatory data, published safety research, and ingredient function analysis.
References
EU CosIng Database
European Commission cosmetic ingredient registry
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Download LuxSenseThis information is for educational purposes only and does not constitute medical advice. Always consult a healthcare professional for skin concerns or allergies.