P-CRESYL 3-OXO-3-PHENYLPROPIONATE
Other
Moderate
CAS Number: 67801-43-8
About P-CRESYL 3-OXO-3-PHENYLPROPIONATE
P-Cresyl 3-Oxo-3-Phenylpropionate is a cosmetic ingredient used in product formulations. Its specific function may vary between products. Exercise caution due to limited available safety data.
Detailed Analysis
p-Cresyl 3-oxo-3-phenylpropionate (also called p-tolyl 3-oxo-3-phenylpropionate) is an ester of p-cresol with phenylpyruvic acid. The compound is listed in the EU CosIng database and used as a fragrance ingredient in cosmetics. The cresol component introduces regulatory attention since p-cresol and its derivatives are subject to assessment under EU Regulation 1223/2009 for phenols and aromatic hydroxy compounds. RIFM and IFRA have assessed this ester and provided use level guidelines to manage any cresol-related toxicity concerns while allowing safe use in fragrance applications.
Skin Benefits
- ✓ Sweet, herbaceous-spicy fragrance with good substantivity
- ✓ Used as a floralizer and fixative in perfume compositions
Known Concerns
- ⚠ Cresol component subject to EU regulatory scrutiny for phenolics
- ⚠ Fragrance allergen declaration thresholds apply
- ⚠ IFRA guidelines control use levels in various product categories
- ⚠ Potential for hydrolysis releasing cresol in skin contact applications
Safety Score
Moderate
Based on EU regulatory data, published safety research, and ingredient function analysis.
References
EU CosIng Database
European Commission cosmetic ingredient registry
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