O-CYMEN-5-OL

65

Moderate

CAS Number: 3228-02-2 / 39660-61-2

About O-CYMEN-5-OL

A preservative related to thymol — effective at keeping products bacteria-free. EU-regulated with a strict 0.1% limit.

Detailed Analysis

o-Cymen-5-ol (4-isopropyl-m-cresol, CAS 3228-02-2) is a phenolic compound used as a cosmetic preservative. EU restricts to 0.1% maximum under Annex V/38. CIR concluded safe up to 0.5%. Concerns include potential neurotoxicity in animal studies at high doses. PubChem CID: 18597.

Skin Benefits

  • ✓ Antimicrobial preservation
  • ✓ Antifungal activity
  • ✓ Product shelf life extension

Known Concerns

  • ⚠ EU Annex V/38 restricted (max 0.1%)
  • ⚠ Neurotoxicity in animal studies at high doses
  • ⚠ Potential skin sensitization

Safety Score

65

Moderate

Based on EU regulatory data, published safety research, and ingredient function analysis.

References

🏛

EU CosIng Database

European Commission cosmetic ingredient registry

⚛

PubChem

National Library of Medicine compound data

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This information is for educational purposes only and does not constitute medical advice. Always consult a healthcare professional for skin concerns or allergies.