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Surfactant

NONOXYNOL-9 PHOSPHATE

CAS 51609-41-7 (generic)/ 66197-78-2
48

Safety score · 0–100

Moderate

Derived from EU CosIng regulatory status, PubChem hazard data and published research. How we score.

A nonylphenol-9 phosphate surfactant. Higher ethoxylation increases impurity risk; nonoxynol-9 is a known mucosal irritant and the underlying NPE is an EU endocrine-disruptor candidate.

Function

SURFACTANT - EMULSIFYINGSURFACTANT - HYDROTROPESURFACTANT - CLEANSING

Skin benefits

  • Effective nonionic phosphate surfactant
  • Cleansing and emulsifying properties
  • Wide industrial use history

Known concerns

  • Nonylphenol ethoxylate base — EU SVHC endocrine disruptor
  • Higher 1,4-dioxane risk than shorter-chain analogs
  • Significant aquatic toxicity
  • Nonoxynol-9 itself is a known mucosal irritant

References

EU

EU CosIng database

European Commission cosmetic ingredient registry: regulatory status, restrictions, authorised functions.

Related surfactants

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This profile is for educational purposes and does not constitute medical advice. Regulatory status and scientific understanding evolve, so always read the physical product label and consult a healthcare professional for personal concerns.