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Skin Conditioning

NICOTIANA BENTHAMIANA HEXAPEPTIDE-40 SH-POLYPEPTIDE-5

CAS 182212-66-4
60

Safety score · 0–100

Fine

Derived from EU CosIng regulatory status, PubChem hazard data and published research. How we score.

A plant-grown recombinant peptide produced in transgenic Nicotiana benthamiana tobacco, fusing TGF-beta-3 mimic with Hexapeptide-40. Eukaryotic processing helps, but residual plant protein contaminants keep it in the cautious-yellow band.

Function

SKIN CONDITIONING

Skin benefits

  • Growth-factor mimicry for renewal signals
  • Eukaryotic folding and modification
  • Animal-free production system

Known concerns

  • Tobacco protein residue can drive sensitization
  • Sparse cosmetic safety literature
  • No SCCS opinion on this fusion

References

EU

EU CosIng database

European Commission cosmetic ingredient registry: regulatory status, restrictions, authorised functions.

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This profile is for educational purposes and does not constitute medical advice. Regulatory status and scientific understanding evolve, so always read the physical product label and consult a healthcare professional for personal concerns.