novel cosmetic active
N-NICOTINOYL TYRAMINE
Safety score · 0–100
Moderate
Derived from EU CosIng regulatory status, PubChem hazard data and published research. How we score.
A nicotinoyl-tyramine conjugate developed as a skin-brightening and tone-evening active, combining niacinamide-style effects with tyramine signalling, with limited published safety data.
Skin benefits
- Nicotinic-acid amide of tyramine investigated as a skin-brightening active
- Combines niacinamide-like effects with tyramine signalling
- Reported reduction in pigmentation and improvement of skin tone
- Lipophilic profile improves stratum corneum delivery
Known concerns
- Limited published cosmetic safety data
- Tyramine has known vasoactive properties at systemic levels
- No CIR, SCCS, or formal regulatory review located
- Long-term tolerance and stability under formulation conditions uncertain
References
EU CosIng database
European Commission cosmetic ingredient registry: regulatory status, restrictions, authorised functions.
Related novel cosmetic actives
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This profile is for educational purposes and does not constitute medical advice. Regulatory status and scientific understanding evolve, so always read the physical product label and consult a healthcare professional for personal concerns.