Solvent
N-Methylacetamide
Safety score · 0–100
Caution
Derived from EU CosIng regulatory status, PubChem hazard data and published research. How we score.
A polar amide solvent with limited cosmetic precedent and class-level concerns for developmental toxicity. Although less acutely toxic than some analogs, it lacks formal cosmetic safety review.
Skin benefits
- Polar solvent useful in chemistry
- Hydrogen bonding capacity
Known concerns
- Animal data suggest developmental toxicity at high doses
- Skin absorption potential
- Limited cosmetic safety review
- Not commonly used in finished cosmetic products
- Amide solvent class often flagged for reproductive concerns
References
EU CosIng database
European Commission cosmetic ingredient registry: regulatory status, restrictions, authorised functions.
Related solvents
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This profile is for educational purposes and does not constitute medical advice. Regulatory status and scientific understanding evolve, so always read the physical product label and consult a healthcare professional for personal concerns.