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Fragrance ingredient

INDOLE

CAS 120-72-9
50

Safety score · 0–100

Moderate

Derived from EU CosIng regulatory status, PubChem hazard data and published research. How we score.

Indole is an aromatic heterocyclic compound used at trace levels in floral perfumery to provide jasmine-like character. GHS hazard data limit acceptable cosmetic concentrations to very low parts per million.

Function

PERFUMING

Skin benefits

  • Used in trace amounts in floral fragrance compositions
  • Provides characteristic jasmine-like animalic note
  • Found naturally in many essential oils

Known concerns

  • GHS classifies indole with acute toxicity hazards at higher exposure
  • Strong odor restricts use to very low cosmetic levels
  • Potential skin and eye irritant
  • Limited tolerance margin for leave-on products

References

EU

EU CosIng database

European Commission cosmetic ingredient registry: regulatory status, restrictions, authorised functions.

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This profile is for educational purposes and does not constitute medical advice. Regulatory status and scientific understanding evolve, so always read the physical product label and consult a healthcare professional for personal concerns.