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Antioxidant / fragrance

HYDROXYMETHYLFURFURAL

CAS 67-47-0
55

Safety score · 0–100

Moderate

Derived from EU CosIng regulatory status, PubChem hazard data and published research. How we score.

5-Hydroxymethylfurfural is a sugar-derived compound with mild antioxidant activity used in fragrance and food. Mixed genotoxicity findings and limited cosmetic review put it in the orange tier.

Skin benefits

  • Natural Maillard-reaction product from sugars
  • Antioxidant activity in some studies
  • Used as fragrance and flavor compound
  • Found in honey and dried fruits

Known concerns

  • Genotoxicity studies show mixed results
  • Can be irritating to mucous membranes
  • Restricted in some food contexts
  • Limited dedicated cosmetic safety review
  • May form sulfated metabolites with mutagenic potential

References

EU

EU CosIng database

European Commission cosmetic ingredient registry: regulatory status, restrictions, authorised functions.

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This profile is for educational purposes and does not constitute medical advice. Regulatory status and scientific understanding evolve, so always read the physical product label and consult a healthcare professional for personal concerns.