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Fragrance ingredient

HEXAHYDRO-DIMETHYLSPIROMETHANONAPHTHALENE-OXIRANE

CAS 41723-98-2 / 41816-03-9
55

Safety score · 0–100

Moderate

Derived from EU CosIng regulatory status, PubChem hazard data and published research. How we score.

Spirocyclic terpenoid epoxide used as a woody-amber fragrance material. The reactive oxirane ring raises potential sensitisation concerns, and dermal toxicology data is limited for this specific isomer pair.

Skin benefits

  • Adds woody, ambery odour notes
  • Long-lasting fragrance fixative properties
  • Stable in alcoholic fragrance bases

Known concerns

  • Epoxide (oxirane) group is an electrophile with sensitisation and genotoxicity flags
  • Limited public toxicology and dermal absorption data
  • Not on EU Annex of approved/restricted substances with explicit allowance
  • Fragrance allergen risk in atopic users

References

EU

EU CosIng database

European Commission cosmetic ingredient registry: regulatory status, restrictions, authorised functions.

Related fragrance ingredients

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This profile is for educational purposes and does not constitute medical advice. Regulatory status and scientific understanding evolve, so always read the physical product label and consult a healthcare professional for personal concerns.