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Antimicrobial

HEXACHLOROPHENE

5

Safety score · 0–100

Avoid

Derived from EU CosIng regulatory status, PubChem hazard data and published research. How we score.

A chlorinated antibacterial banned from EU cosmetics under Annex II due to neurotoxicity and skin absorption. Implicated in historic infant deaths; not permitted in modern cosmetic formulations.

Function

PRESERVATIVE

Skin benefits

  • Historically used as antibacterial preservative
  • Effective against gram-positive bacteria

Known concerns

  • EU Annex II prohibited substance — banned in cosmetics
  • Neurotoxic; absorbed through skin
  • Linked to historical infant deaths from talc contamination
  • Restricted to medical use only under strict supervision

References

EU

EU CosIng database

European Commission cosmetic ingredient registry: regulatory status, restrictions, authorised functions.

Related antimicrobials

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This profile is for educational purposes and does not constitute medical advice. Regulatory status and scientific understanding evolve, so always read the physical product label and consult a healthcare professional for personal concerns.