HC BLUE NO. 12

Other

50

Moderate

CAS Number: 132885-85-9 / 104516-93-0

About HC BLUE NO. 12

A hair dye intermediate listed in EU Annex III (entry III/225) with permitted use conditions, primarily used in oxidative hair dye formulations at controlled concentrations.

Detailed Analysis

HC Blue No. 12 is an aromatic heterocyclic amine-type hair dye intermediate listed in EU CosIng Annex III under entry III/225, which sets specific conditions and concentration limits for its use in cosmetic products. It is restricted to oxidative (permanent) hair dye formulations only and may not be used in products that can be applied to the oral mucosa. The restriction aims to limit exposure given potential sensitization concerns typical of hair dye intermediates.

Known Concerns

  • EU Annex III restricted hair dye intermediate (III/225)
  • Potential skin sensitization from aromatic amine exposure
  • Restricted to oxidative hair dye use only

Safety Score

50

Moderate

Based on EU regulatory data, published safety research, and ingredient function analysis.

References

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EU CosIng Database

European Commission cosmetic ingredient registry

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This information is for educational purposes only and does not constitute medical advice. Always consult a healthcare professional for skin concerns or allergies.