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ETHYL 2,4-DICARBOETHOXY PANTOTHENATE

CAS 16473-77-1
83

Safety score · 0–100

Good

Derived from EU CosIng regulatory status, PubChem hazard data and published research. How we score.

Ethyl 2,4-dicarboethoxy Pantothenate is a cosmetic ingredient used in product formulations. Exercise caution due to limited available safety data.

Ethyl 2,4-Dicarboethoxy Pantothenate is a doubly esterified pantothenic acid (vitamin B5) derivative listed on EU CosIng as a skin-conditioning agent. The ethyl ester of the carboxylic acid groups improves lipid solubility and skin penetration compared to panthenol. Pantothenic acid derivatives are widely used and well-tolerated in cosmetics. No EU Annex II or III restrictions apply. The dicarboethoxy substitution increases metabolic stability, prolonging the active vitamin B5 effect on skin.

Skin benefits

  • Deep skin hydration and conditioning
  • Supports skin barrier repair
  • Anti-inflammatory properties from provitamin B5 activity

Known concerns

  • Generally very safe; no EU restrictions
  • Possible mild skin irritation in extremely sensitive individuals
  • High concentrations may feel slightly oily on skin

References

EU

EU CosIng database

European Commission cosmetic ingredient registry: regulatory status, restrictions, authorised functions.

Related others

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This profile is for educational purposes and does not constitute medical advice. Regulatory status and scientific understanding evolve, so always read the physical product label and consult a healthcare professional for personal concerns.