(Epoxyethyl)benzene (Styrene oxide)
Avoid
CAS Number: 96-09-3
About (Epoxyethyl)benzene (Styrene oxide)
An epoxide compound classified as a probable human carcinogen and mutagen, banned from cosmetic use in the EU due to severe genotoxicity and organ toxicity concerns.
Detailed Analysis
(Epoxyethyl)benzene, commonly known as styrene oxide (CAS 96-09-3), is an epoxide derived from styrene metabolism. EU Regulation 1223/2009 Annex III restricts its use to concentrations below 0.1% as a constituent of substances or mixtures. The compound carries extensive hazard statements including H227 (combustible), H302/H312/H332 (harmful if swallowed, in contact with skin, or if inhaled), H315/H317/H319/H335 (irritation and sensitization), H340 (may cause genetic defects), H341 (suspected of causing genetic defects), H350 (may cause cancer), H361 (suspected of reproductive toxicity), H370/H372 (organ toxicity), and H401/H412 (aquatic toxicity). It is classified as a Group 2A probable human carcinogen by IARC.
Known Concerns
- ⚠ EU Annex III restricted - probable carcinogen
- ⚠ Confirmed mutagen (H340)
- ⚠ Suspected carcinogen (H350)
- ⚠ Reproductive toxicity (H361)
- ⚠ Organ toxicity (H370/H372)
- ⚠ Extensive hazard profile
Safety Score
Avoid
Based on EU regulatory data, published safety research, and ingredient function analysis.
References
EU CosIng Database
European Commission cosmetic ingredient registry
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