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DEER ANTLER CELL/SH-POLYPEPTIDE-1 CONDITIONED MEDIA

28

Safety score · 0–100

Caution

Derived from EU CosIng regulatory status, PubChem hazard data and published research. How we score.

A biologically derived ingredient from deer antler cell cultures that raises significant regulatory and safety concerns in the EU due to BSE/TSE risk from animal-derived materials.

This ingredient is explicitly flagged in EU CosIng with a restriction note referencing Entry 419 of Annex II to Regulation 1223/2009, which prohibits Category 1 and Category 2 materials as defined in Regulation (EC) No 1069/2009 (the Animal By-Products Regulation). Deer antler cells and conditioned media fall under animal by-products requiring strict sourcing controls. The sh-Polypeptide-1 component (a growth factor analog) further raises concerns about uncontrolled biological activity. Use in EU cosmetics requires compliance with the full Animal By-Products regulatory framework, which effectively restricts or prohibits this ingredient.

Known concerns

  • EU Annex II restriction (Entry 419 - animal by-products)
  • BSE/TSE risk from animal-derived material
  • Regulation (EC) No 1069/2009 compliance required
  • Biological activity of growth factors may be uncontrolled

References

EU

EU CosIng database

European Commission cosmetic ingredient registry: regulatory status, restrictions, authorised functions.

Same plant / compound family

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This profile is for educational purposes and does not constitute medical advice. Regulatory status and scientific understanding evolve, so always read the physical product label and consult a healthcare professional for personal concerns.