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Emollient

CYCLOTETRASILOXANE

CAS 556-67-2 / 293-51-6
5

Safety score · 0–100

Avoid

Derived from EU CosIng regulatory status, PubChem hazard data and published research. How we score.

D4 (cyclotetrasiloxane) — banned in EU cosmetics under REACH/Annex II as a suspected reproductive toxicant, endocrine disruptor and persistent environmental pollutant. One of the most restricted silicones globally.

Skin benefits

  • Light, fast-evaporating silicone feel — historically used to give smooth slip

Known concerns

  • BANNED in EU cosmetics (Annex II / REACH restriction)
  • Reproductive toxicity classification (Repr. 2)
  • Endocrine disruption concerns
  • Persistent, bioaccumulative, environmental pollutant
  • Aquatic toxicity

References

EU

EU CosIng database

European Commission cosmetic ingredient registry: regulatory status, restrictions, authorised functions.

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This profile is for educational purposes and does not constitute medical advice. Regulatory status and scientific understanding evolve, so always read the physical product label and consult a healthcare professional for personal concerns.