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Emollient

CYCLOHEXASILOXANE

CAS 540-97-6
45

Safety score Β· 0–100

Moderate

Derived from EU CosIng regulatory status, PubChem hazard data and published research. How we score.

D6 cyclic silicone β€” gives products a silky, lightweight feel. Skin-safe but the EU classifies it as PBT (persistent, bioaccumulative, toxic) and it's being phased out by 2026-2027.

Skin benefits

  • Volatile, silky silicone β€” leaves no residue
  • Improves spreadability of pigments and sunscreens
  • Fast evaporating, low irritation

Known concerns

  • EU PBT/vPvB substance β€” environmentally persistent
  • Phase-out underway under REACH restrictions
  • Bioaccumulation concerns in aquatic systems

References

EU

EU CosIng database

European Commission cosmetic ingredient registry: regulatory status, restrictions, authorised functions.

PC

PubChem

U.S. NIH compound data, GHS hazard codes and toxicity literature.

View β†’

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This profile is for educational purposes and does not constitute medical advice. Regulatory status and scientific understanding evolve, so always read the physical product label and consult a healthcare professional for personal concerns.