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CIS-3-HEXENYL SALICYLATE

CAS 65405-77-8
74

Safety score · 0–100

Fine

Derived from EU CosIng regulatory status, PubChem hazard data and published research. How we score.

A salicylate ester of cis-3-hexenol providing UV-protective and warm floral-green fragrance notes. While salicylates are under regulatory scrutiny, this specific compound is not banned or severely restricted under EU cosmetics law.

Cis-3-hexenyl salicylate is the ester of leaf alcohol (cis-3-hexen-1-ol) with salicylic acid. Salicylates in general are subject to EU restrictions due to their potential for skin sensitization and absorption — notably, salicylic acid is restricted in EU Annex III for use in cosmetic products above certain concentrations. However, cis-3-hexenyl salicylate as a fragrance ingredient is not individually listed in EU Annex II (banned) or Annex III (restricted). IFRA standards apply and recommend maximum use levels. The salicylate group confers mild UV-absorbing properties.

Skin benefits

  • Fragrance material with mild UV-absorbing properties
  • Warm, sweet-green floral character

Known concerns

  • Skin sensitizer — salicylate class concern
  • IFRA recommended restrictions
  • Salicylate structure may contribute to overall salicylate load in formulations
  • Potential for skin absorption

References

EU

EU CosIng database

European Commission cosmetic ingredient registry: regulatory status, restrictions, authorised functions.

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This profile is for educational purposes and does not constitute medical advice. Regulatory status and scientific understanding evolve, so always read the physical product label and consult a healthcare professional for personal concerns.