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Formaldehyde-releasing preservative

Cis-1-(3-chloroallyl)-3,5,7- triaza-1-azoniaadamantane chloride (cis-CTAC)

CAS 51229-78-8
25

Safety score · 0–100

Caution

Derived from EU CosIng regulatory status, PubChem hazard data and published research. How we score.

Quaternium-15 (cis-CTAC) is a formaldehyde-releasing preservative used in some leave-on and rinse-off products. Dermatologists rank it among the most common contact allergens, and EU restrictions are very tight.

Skin benefits

  • Broad-spectrum antimicrobial preservative
  • Effective against bacteria and fungi

Known concerns

  • Toxic if swallowed or in contact with skin
  • Strong skin sensitizer / formaldehyde releaser
  • Suspected reproductive toxicant
  • Often top contact allergen in dermatology clinics

References

EU

EU CosIng database

European Commission cosmetic ingredient registry: regulatory status, restrictions, authorised functions.

Related formaldehyde-releasing preservatives

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This profile is for educational purposes and does not constitute medical advice. Regulatory status and scientific understanding evolve, so always read the physical product label and consult a healthcare professional for personal concerns.