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Preservative

CHLOROXYLENOL

CAS 88-04-0 / 1321-23-9
40

Safety score · 0–100

Moderate

Derived from EU CosIng regulatory status, PubChem hazard data and published research. How we score.

A chlorinated phenolic antiseptic (PCMX) used as a preservative in rinse-off cosmetics. Effective antimicrobial but with documented sensitization, so EU caps it and leave-on use is discouraged.

Skin benefits

  • Effective broad-spectrum antimicrobial
  • Used at low % as preservative
  • Long history in antiseptic products

Known concerns

  • Skin sensitization risk
  • Restricted concentration in EU cosmetics
  • Eye irritation in concentrated form
  • Aquatic toxicity

References

EU

EU CosIng database

European Commission cosmetic ingredient registry: regulatory status, restrictions, authorised functions.

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This profile is for educational purposes and does not constitute medical advice. Regulatory status and scientific understanding evolve, so always read the physical product label and consult a healthcare professional for personal concerns.