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Antimicrobial

CHLORHEXIDINE

CAS 55-56-1
55

Safety score · 0–100

Moderate

Derived from EU CosIng regulatory status, PubChem hazard data and published research. How we score.

A potent antiseptic biguanide used at low levels as a preservative. Effective but a known sensitizer; the EU caps cosmetic use at 0.3% to manage allergy and eye risk.

Skin benefits

  • Powerful broad-spectrum antimicrobial
  • Effective preservative at low levels
  • Used in medical antiseptics

Known concerns

  • Documented contact dermatitis and rare anaphylaxis
  • Eye toxicity if misused
  • EU restricts to 0.3% in leave-on cosmetics

References

EU

EU CosIng database

European Commission cosmetic ingredient registry: regulatory status, restrictions, authorised functions.

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This profile is for educational purposes and does not constitute medical advice. Regulatory status and scientific understanding evolve, so always read the physical product label and consult a healthcare professional for personal concerns.