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Preservative

CHLORHEXIDINE DIHYDROCHLORIDE

CAS 3697-42-5
55

Safety score · 0–100

Moderate

Derived from EU CosIng regulatory status, PubChem hazard data and published research. How we score.

Chlorhexidine dihydrochloride, a strong antiseptic and preservative also used in mouthwashes. Effective but a known sensitizer with rare cases of severe allergic reaction.

Function

ANTIMICROBIALORAL CAREPRESERVATIVE

Skin benefits

  • Effective antimicrobial preservative
  • Useful against gram-positive bacteria
  • Long medical-use track record

Known concerns

  • Documented contact allergen and sensitizer
  • Rare but serious anaphylactic reactions reported
  • EU concentration limits apply

References

EU

EU CosIng database

European Commission cosmetic ingredient registry: regulatory status, restrictions, authorised functions.

PC

PubChem

U.S. NIH compound data, GHS hazard codes and toxicity literature.

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This profile is for educational purposes and does not constitute medical advice. Regulatory status and scientific understanding evolve, so always read the physical product label and consult a healthcare professional for personal concerns.