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Skin lipid / ceramide

CERAMIDE AS

CAS 100403-19-8
88

Safety score · 0–100

Good

Derived from EU CosIng regulatory status, PubChem hazard data and published research. How we score.

Ceramide AS is an alpha-hydroxy sphingosine-based skin-barrier lipid used to mimic endogenous ceramides, supporting barrier repair, hydration and reduced transepidermal water loss in skincare.

Function

HAIR CONDITIONINGSKIN CONDITIONING

Skin benefits

  • Natural skin-barrier lipid mimicking endogenous stratum corneum ceramides
  • Reduces transepidermal water loss and supports barrier repair
  • CIR Expert Panel concluded ceramides safe in cosmetics at current use levels
  • Strong tolerance in human patch testing across ceramide subclasses

Known concerns

  • Effective only at proper formulation and delivery, requires solvent or liposomal carrier
  • Sourcing and synthesis purity can vary by supplier
  • Premium cost may limit effective in-use concentration
  • Stability requires protection from oxidation in some bases

References

EU

EU CosIng database

European Commission cosmetic ingredient registry: regulatory status, restrictions, authorised functions.

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This profile is for educational purposes and does not constitute medical advice. Regulatory status and scientific understanding evolve, so always read the physical product label and consult a healthcare professional for personal concerns.