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Humectant

CALCIUM POLYGAMMA-GLUTAMATE

CAS 648426-24-8
88

Safety score · 0–100

Good

Derived from EU CosIng regulatory status, PubChem hazard data and published research. How we score.

A calcium salt of poly-gamma-glutamic acid (a polymer of glutamic acid produced by Bacillus natto). Acts as a powerful humectant and skin smoother with no documented safety concerns at cosmetic levels.

Function

SKIN CONDITIONING

Skin benefits

  • High water-binding capacity humectant
  • Bioderived from natto fermentation
  • Skin smoothing
  • Compatible with most actives

Known concerns

  • Limited cosmetic-specific publications
  • Possible iodine/marine traces in some sources

References

EU

EU CosIng database

European Commission cosmetic ingredient registry: regulatory status, restrictions, authorised functions.

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FRUCTOSE
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HYALURONIC ACID/PEG-800 CROSSPOLYMER
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HYDROLYZED AGAROSE
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This profile is for educational purposes and does not constitute medical advice. Regulatory status and scientific understanding evolve, so always read the physical product label and consult a healthcare professional for personal concerns.