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Antioxidant

ANNONA MURICATA LEAF/STEM EXTRACT

48

Safety score · 0–100

Moderate

Derived from EU CosIng regulatory status, PubChem hazard data and published research. How we score.

Graviola (soursop) leaf and stem extract — contains annonaceous acetogenins linked to atypical Parkinsonism in epidemiological studies. Cosmetic safety hinges on supplier acetogenin removal.

Function

SKIN CONDITIONING

Skin benefits

  • Phenolic antioxidant chemistry
  • Traditional Caribbean and Latin American medicinal use
  • Mild antimicrobial activity

Known concerns

  • Contains annonaceous acetogenins — neurotoxins linked to atypical Parkinsonism in epidemiology
  • Documented neurotoxicity from chronic graviola consumption
  • Cosmetic safety dependent on acetogenin removal
  • Limited cosmetic dossiers

References

EU

EU CosIng database

European Commission cosmetic ingredient registry: regulatory status, restrictions, authorised functions.

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PHENYLTHIOGLYCOLIC ACID
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Same plant / compound family

55
ANNONA MURICATA BARK EXTRACT
Skin Conditioning
 80
ANNONA MURICATA CALLUS LYSATE EXTRACT
Antioxidant
 58
ANNONA MURICATA FRUIT
Botanical fruit extract
 58
ANNONA MURICATA FRUIT EXTRACT
Skin Conditioning
 50
ANNONA MURICATA LEAF EXTRACT
Skin Conditioning
 58
ANNONA MURICATA SEEDCAKE POWDER

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This profile is for educational purposes and does not constitute medical advice. Regulatory status and scientific understanding evolve, so always read the physical product label and consult a healthcare professional for personal concerns.