Other
ANDROGRAPHOLIDE
Safety score · 0–100
Good
Derived from EU CosIng regulatory status, PubChem hazard data and published research. How we score.
A diterpenoid lactone from the herb Andrographis paniculata with well-documented anti-inflammatory and antioxidant skin benefits.
Andrographolide is the principal bioactive diterpenoid from Andrographis paniculata, widely used in traditional medicine and increasingly in cosmetic formulations for its potent anti-inflammatory, antioxidant, and anti-aging properties. It is listed in CosIng and is a permitted cosmetic ingredient in the EU. While generally safe, andrographolide can be a moderate skin irritant at high concentrations and may cause allergic reactions in sensitive individuals. Its safety at cosmetic-use concentrations is well supported by available data.
Skin benefits
- Potent anti-inflammatory activity
- Antioxidant protection
- Anti-aging and collagen-supporting properties
- Antimicrobial benefits
Known concerns
- May be a moderate skin irritant at high concentrations
- Rare allergic/sensitization reactions possible
- Safety at very high concentrations not fully established
References
EU CosIng database
European Commission cosmetic ingredient registry: regulatory status, restrictions, authorised functions.
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This profile is for educational purposes and does not constitute medical advice. Regulatory status and scientific understanding evolve, so always read the physical product label and consult a healthcare professional for personal concerns.