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Solvent

Acetonitrile

CAS 75-05-8
8

Safety score · 0–100

Avoid

Derived from EU CosIng regulatory status, PubChem hazard data and published research. How we score.

Acetonitrile — a polar aprotic solvent used in HPLC and synthesis. Banned in EU cosmetics under Annex II; metabolizes to cyanide and is acutely toxic.

Skin benefits

  • No cosmetic use (laboratory solvent)

Known concerns

  • EU Annex II banned in cosmetics
  • Metabolizes to cyanide on systemic exposure
  • Acutely toxic if inhaled or ingested
  • Eye and skin irritant

References

EU

EU CosIng database

European Commission cosmetic ingredient registry: regulatory status, restrictions, authorised functions.

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This profile is for educational purposes and does not constitute medical advice. Regulatory status and scientific understanding evolve, so always read the physical product label and consult a healthcare professional for personal concerns.