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ACETOIN

CAS 513-86-0
82

Safety score · 0–100

Good

Derived from EU CosIng regulatory status, PubChem hazard data and published research. How we score.

A naturally occurring ketone (diacetyl derivative) widely used as a flavour and fragrance ingredient; low toxicity with only minor sensitisation potential at high concentrations.

Acetoin (CAS 513-86-0), also known as 3-hydroxy-2-butanone, is a small aliphatic ketone that occurs naturally in butter, strawberries, and other foods. It is approved as a flavouring substance (FEMA GRAS) and used in cosmetics as a fragrance ingredient and pH buffer component. The compound shows low acute toxicity and is not a significant irritant or sensitiser at typical cosmetic use levels. EU regulation does not impose restrictions on acetoin in cosmetic formulations.

Skin benefits

  • Fragrance ingredient — imparts pleasant sensory profile to formulations
  • pH buffering — contributes to formulation stability
  • Low irritation potential at cosmetic use levels

Known concerns

  • Minor fragrance allergen potential at very high concentrations
  • Oxidises to diacetyl (butter flavour) on exposure to air — secondary exposure consideration

References

EU

EU CosIng database

European Commission cosmetic ingredient registry: regulatory status, restrictions, authorised functions.

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This profile is for educational purposes and does not constitute medical advice. Regulatory status and scientific understanding evolve, so always read the physical product label and consult a healthcare professional for personal concerns.