7-Methoxycoumarin, when used as a fragrance ingredient
Other
Moderate
CAS Number: 531-59-9
About 7-Methoxycoumarin, when used as a fragrance ingredient
A naturally occurring coumarin derivative with photosensitisation and skin sensitisation potential, requiring EU Annex III compliance and IFRA restriction.
Detailed Analysis
7-Methoxycoumarin occurs naturally in citrus and lavender oils but is regulated when used as an intentionally added fragrance ingredient. It is listed in EU Annex III as a restricted fragrance allergen; the photosensitising potential of coumarin derivatives (even 7-substituted ones) is well documented, and IFRA recommends maximum use levels of 15 ppm in various product categories. The methoxy group reduces but does not eliminate photosensitising activity compared to unsubstituted coumarin.
Known Concerns
- ⚠ Photosensitisation potential — coumarin derivative
- ⚠ Skin sensitisation reported
- ⚠ EU Annex III restricted fragrance allergen
Safety Score
Moderate
Based on EU regulatory data, published safety research, and ingredient function analysis.
References
EU CosIng Database
European Commission cosmetic ingredient registry
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