7-DEHYDROCHOLESTEROL

82

Good

CAS Number: 434-16-2

About 7-DEHYDROCHOLESTEROL

A vitamin D precursor that converts to active vitamin D3 upon UV exposure, used in skincare for its barrier-supporting properties.

Detailed Analysis

7-Dehydrocholesterol (cholesta-5,7-dien-3-beta-ol) is the biological precursor of vitamin D3 (cholecalciferol) and is naturally present in the epidermis. When used in cosmetic formulations and exposed to UV radiation, it converts to vitamin D3. It is listed in EU CosIng and is considered safe for cosmetic use at appropriate concentrations. As a precursor to a nutrient with hormonal activity, concentrations should be controlled to avoid excessive vitamin D synthesis from UV conversion.

Skin Benefits

  • Supports skin barrier function and homeostasis
  • Natural precursor to vitamin D3 with potential barrier-strengthening effects

Known Concerns

  • Converts to vitamin D3 upon UV exposure — control of residual levels required

Safety Score

82

Good

Based on EU regulatory data, published safety research, and ingredient function analysis.

References

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EU CosIng Database

European Commission cosmetic ingredient registry

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This information is for educational purposes only and does not constitute medical advice. Always consult a healthcare professional for skin concerns or allergies.