6-Amino-o-cresol and its salts, when used as a substance in hair dye products
Other
Caution
CAS Number: 17672-22-9
About 6-Amino-o-cresol and its salts, when used as a substance in hair dye products
An aromatic amine hair dye intermediate with documented respiratory and skin sensitization hazards requiring professional use restrictions under EU regulations.
Detailed Analysis
6-Amino-o-cresol is a cresol-derived aromatic amine used as a primary intermediate in oxidative hair dye systems. Under EU Regulation 1223/2009, Annex III, its use is restricted to professional hair dye products only, reflecting significant concerns identified by the SCCS regarding respiratory sensitization. GHS hazard statements (H302, H315, H319, H335) indicate acute oral toxicity, skin and eye irritation, and specific target organ toxicity via inhalation. The o-cresol structure contributes to its systemic toxicity profile, and the signal word 'Warning' is required on labels. Consumer self-use products are prohibited.
Known Concerns
- ⚠ Respiratory sensitizer (H335)
- ⚠ Skin sensitizer (H315)
- ⚠ Acute oral toxicity (H302)
- ⚠ EU Annex III professional-use restriction
- ⚠ Eye irritation hazard (H319)
Safety Score
Caution
Based on EU regulatory data, published safety research, and ingredient function analysis.
References
EU CosIng Database
European Commission cosmetic ingredient registry
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