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Colorant

4-NITRO-O-PHENYLENEDIAMINE SULFATE

CAS 68239-82-7
20

Safety score · 0–100

Caution

Derived from EU CosIng regulatory status, PubChem hazard data and published research. How we score.

A nitro-aromatic oxidative hair dye intermediate. Known skin sensitizer, EU-restricted in hair dyes, with historical mutagenicity flags; strictly off-skin use only.

Function

HAIR DYEING

Skin benefits

  • Brown/red oxidative hair-dye coupler
  • Effective at low % in dye blends

Known concerns

  • Strong skin sensitizer — patch test required
  • EU restricted (Annex III hair dye limits)
  • Mutagenicity signals in older Ames data
  • Eye irritant

References

EU

EU CosIng database

European Commission cosmetic ingredient registry: regulatory status, restrictions, authorised functions.

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This profile is for educational purposes and does not constitute medical advice. Regulatory status and scientific understanding evolve, so always read the physical product label and consult a healthcare professional for personal concerns.