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Prohibited aromatic amine

4-Methyl-m-phenylenediamine (Toluene-2,4-diamine) and its salts

CAS 95-80-7
4

Safety score · 0–100

Avoid

Derived from EU CosIng regulatory status, PubChem hazard data and published research. How we score.

Toluene-2,4-diamine is a banned hair dye chemical classified as a probable human carcinogen. The EU prohibits it from all cosmetics because of cancer, allergy, and reproductive toxicity concerns.

Skin benefits

  • Historically used as a permanent hair dye intermediate
  • Of regulatory interest because it appeared in older formulations

Known concerns

  • Classified as Carc. 1B and Muta. 2 under EU CLP
  • Banned in EU cosmetics (Annex II)
  • Strong skin sensitizer with high rate of allergic contact dermatitis
  • Toxic to reproduction based on regulatory assessments

References

EU

EU CosIng database

European Commission cosmetic ingredient registry: regulatory status, restrictions, authorised functions.

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This profile is for educational purposes and does not constitute medical advice. Regulatory status and scientific understanding evolve, so always read the physical product label and consult a healthcare professional for personal concerns.