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Banned hydrazine intermediate

(4-Hydrazinophenyl)-N-methylmethanesulfonamide hydrochloride

CAS 81880-96-8
6

Safety score · 0–100

Avoid

Derived from EU CosIng regulatory status, PubChem hazard data and published research. How we score.

A hydrazine-bearing pharmaceutical intermediate used in synthesis of triptan drugs. Hydrazines are toxic and suspected carcinogens, and this compound is not appropriate for any cosmetic application.

Skin benefits

  • Pharmaceutical synthesis intermediate (sumatriptan precursor)
  • No cosmetic role

Known concerns

  • Hydrazine derivatives are classified as suspected carcinogens
  • High intrinsic reactivity and toxicity
  • Not approved for cosmetic use anywhere
  • EU CMR considerations bar use in consumer products

References

EU

EU CosIng database

European Commission cosmetic ingredient registry: regulatory status, restrictions, authorised functions.

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This profile is for educational purposes and does not constitute medical advice. Regulatory status and scientific understanding evolve, so always read the physical product label and consult a healthcare professional for personal concerns.