4,4'-Oxydianiline (p-aminophenyl ether) and its salts
Other
Avoid
CAS Number: 101-80-4
About 4,4'-Oxydianiline (p-aminophenyl ether) and its salts
A cosmetic ingredient. Its specific function may vary between products. Exercise caution due to limited available safety data.
Detailed Analysis
4,4'-Oxydianiline (CAS 101-80-4) is an aromatic diamine with a suspected carcinogenic and mutagenic profile (CMR Category 1B under CLP Regulation EC 1272/2008). It is listed in EU Cosmetics Regulation Annex II — the list of substances prohibited in cosmetic products — meaning its use in any cosmetic formulation is expressly forbidden in the European Union regardless of concentration.
Known Concerns
- ⚠ EU Annex II — prohibited substance (carcinogenic/mutagenic)
- ⚠ CMR Category 1B under CLP Regulation
- ⚠ Confirmed reproductive toxicity
- ⚠ Skin absorption potential
- ⚠ Not permitted in any cosmetic product in the EU
Safety Score
Avoid
Based on EU regulatory data, published safety research, and ingredient function analysis.
References
EU CosIng Database
European Commission cosmetic ingredient registry
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