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4-[(2-Hydroxyethyl)amino-3-nitrophenol

CAS 65235-31-6
40

Safety score · 0–100

Moderate

Derived from EU CosIng regulatory status, PubChem hazard data and published research. How we score.

4-[(2-hydroxyethyl)amino-3-nitrophenol is a cosmetic ingredient used in product formulations. Exercise caution due to limited available safety data.

This nitro-phenol with a hydroxyethylamino substituent carries multiple hazard statements including H361d (suspected reproductive/developmental toxicity) and H411 (aquatic toxicity), alongside skin sensitization and irritation. Used at maximum 1.85% in hair dyes, the combination of reproductive toxicity concern with sensitization hazards places significant restrictions on its use in consumer products.

Known concerns

  • Suspected reproductive/developmental toxicity (H361d)
  • Skin sensitizer (H317)
  • Skin and eye irritation (H315, H319)
  • Aquatic toxicity (H411)
  • Oral toxicity (H302)

References

EU

EU CosIng database

European Commission cosmetic ingredient registry: regulatory status, restrictions, authorised functions.

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This profile is for educational purposes and does not constitute medical advice. Regulatory status and scientific understanding evolve, so always read the physical product label and consult a healthcare professional for personal concerns.