(3-Chlorophenyl)-(4-methoxy-3-nitrophenyl)methanone

22

Avoid

CAS Number: 66938-41-8

About (3-Chlorophenyl)-(4-methoxy-3-nitrophenyl)methanone

(3-Chlorophenyl)-(4-methoxy-3-nitrophenyl)methanone is a cosmetic ingredient used in product formulation. Exercise caution due to limited available safety data.

Detailed Analysis

This substituted benzophenone ketone carries hazard classifications H341 (suspected of causing genetic defects), H400 (very toxic to aquatic life), and H410 (very toxic to aquatic life with long-lasting effects) under CLP Regulation. The presence of both a nitro group and a chloro substituent significantly increases toxicological concern. The compound is not listed in CosIng as an approved cosmetic ingredient and would require extensive safety evaluation before any cosmetic use. Its mutagenic potential (H341) is a primary red flag for dermal exposure risk.

Known Concerns

  • ⚠ H341 - suspected mutagen/genotoxic concern
  • ⚠ H400/H410 - very toxic to aquatic environment
  • ⚠ Nitro-chloro substitution pattern increases toxicity
  • ⚠ Not approved for cosmetic use in EU

Safety Score

22

Avoid

Based on EU regulatory data, published safety research, and ingredient function analysis.

References

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EU CosIng Database

European Commission cosmetic ingredient registry

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This information is for educational purposes only and does not constitute medical advice. Always consult a healthcare professional for skin concerns or allergies.