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Skin Conditioning

2-OLEAMIDO-1,3-OCTADECANEDIOL

CAS 54422-45-6
80

Safety score · 0–100

Good

Derived from EU CosIng regulatory status, PubChem hazard data and published research. How we score.

A synthetic skin-barrier lipid (pseudoceramide) that mimics natural ceramides. Used in barrier-repair creams; structurally similar to skin lipids and considered well tolerated.

Skin benefits

  • Synthetic ceramide-like skin lipid
  • Helps repair the skin barrier
  • Locks in moisture and reduces transepidermal water loss

Known concerns

  • Premium ingredient; limited public dossier
  • No significant safety concerns at cosmetic concentrations

References

EU

EU CosIng database

European Commission cosmetic ingredient registry: regulatory status, restrictions, authorised functions.

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This profile is for educational purposes and does not constitute medical advice. Regulatory status and scientific understanding evolve, so always read the physical product label and consult a healthcare professional for personal concerns.