(2-Chloroethyl)(3-hydroxypropyl)ammonium chloride

20

Avoid

CAS Number: 40722-80-3

About (2-Chloroethyl)(3-hydroxypropyl)ammonium chloride

(2-Chloroethyl)(3-hydroxypropyl)ammonium chloride is a cosmetic ingredient used in product formulation. Exercise caution due to limited available safety data.

Detailed Analysis

(2-Chloroethyl)(3-hydroxypropyl)ammonium chloride carries H317 (skin sensitizer), H340 (suspected mutagen), H350 (suspected carcinogen), and H373 (specific organ toxicity) classifications. The 2-chloroethyl group is a well-known alkylating agent alert associated with mutagenicity and carcinogenicity. It is not listed in EU cosmetic regulation Annexes but its severe hazard profile absolutely contraindicates cosmetic use. The combination of sensitizing, mutagenic, and carcinogenic potential makes this compound one of the most concerning in this batch.

Known Concerns

  • ⚠ Suspected mutagen (H340)
  • ⚠ Suspected carcinogen (H350)
  • ⚠ Skin sensitizer (H317)
  • ⚠ Specific organ toxicity (H373)
  • ⚠ Chlorinated alkylating agent

Safety Score

20

Avoid

Based on EU regulatory data, published safety research, and ingredient function analysis.

References

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EU CosIng Database

European Commission cosmetic ingredient registry

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This information is for educational purposes only and does not constitute medical advice. Always consult a healthcare professional for skin concerns or allergies.