Fragrance
2,4-XYLENOL
Safety score · 0–100
Avoid
Derived from EU CosIng regulatory status, PubChem hazard data and published research. How we score.
A dimethylphenol — corrosive, acutely toxic by skin contact and ingestion. In the cresol/xylenol class of industrial phenolics that are not appropriate for cosmetic use.
2,4-Xylenol (2,4-dimethylphenol, CAS 105-67-9) is a dimethyl-substituted phenol in the cresol/xylenol family. It is widely recognized as corrosive and systemically toxic: standard GHS classifications include skin corrosion Category 1B (H314), acute toxicity Category 3 by oral/dermal/inhalation (H301/H311/H331), and acute aquatic toxicity. Substituted phenols penetrate skin efficiently and cause systemic phenolic toxicity including CNS depression and methemoglobinemia. No CIR/SCCS monograph supports cosmetic use. Potentially present only as a trace impurity in some natural extracts; not an intentional cosmetic fragrance material at meaningful levels.
Function
Skin benefits
- No significant benefits at cosmetic levels
Known concerns
- Corrosive phenol
- Acute systemic toxicity
- Skin penetration
- Aquatic hazard
References
EU CosIng database
European Commission cosmetic ingredient registry: regulatory status, restrictions, authorised functions.
Related fragrances
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This profile is for educational purposes and does not constitute medical advice. Regulatory status and scientific understanding evolve, so always read the physical product label and consult a healthcare professional for personal concerns.