2,2'-METHYLENEBIS 4-AMINOPHENOL

Other

25

Avoid

CAS Number: 63969-46-0

About 2,2'-METHYLENEBIS 4-AMINOPHENOL

2,2'-methylenebis 4-aminophenol is a cosmetic ingredient used in product formulations. Exercise caution due to limited available safety data.

Detailed Analysis

2,2'-Methylenebis 4-Aminophenol is a hair dye intermediate with structural alerts for respiratory sensitisation, skin sensitisation, and environmental hazard (H400/H410 aquatic toxicity). While not explicitly listed in EU Annex II or III from the available CoSing data, its hazard profile — including serious eye damage, specific target organ toxicity, and aquatic toxicity — makes it a compound of concern requiring careful safety evaluation before cosmetic use.

Known Concerns

  • Respiratory sensitisation potential
  • Serious eye damage (H318)
  • Skin sensitisation
  • Aquatic toxicity H400/H410
  • Specific target organ toxicity (STOT)

Safety Score

25

Avoid

Based on EU regulatory data, published safety research, and ingredient function analysis.

References

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EU CosIng Database

European Commission cosmetic ingredient registry

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This information is for educational purposes only and does not constitute medical advice. Always consult a healthcare professional for skin concerns or allergies.