2,2'-METHYLENEBIS-4-AMINOPHENOL HCL

Other

18

Avoid

CAS Number: 27311-52-0

About 2,2'-METHYLENEBIS-4-AMINOPHENOL HCL

2,2'-methylenebis-4-aminophenol Hcl is a cosmetic ingredient used in product formulations. Exercise caution due to limited available safety data.

Detailed Analysis

This HCl salt of 2,2'-Methylenebis-4-aminophenol carries a 'Danger' signal word with multiple severe hazard classifications: H300 (acute toxicity if swallowed), H319 (serious eye damage), H372 (specific target organ toxicity — repeated exposure), and H400/H410 (acute aquatic toxicity). The aromatic diamine structure is a known sensitiser and poses risks of respiratory sensitisation. Its unsuitability for cosmetic use is reflected in its severe hazard profile, and it would require explicit EU approval if used at all — which appears unlikely given these signals.

Known Concerns

  • ACUTE TOXICITY if swallowed (H300)
  • Serious eye damage (H319)
  • Specific target organ toxicity — repeated exposure (H372)
  • Acute aquatic toxicity (H400)
  • Chronic aquatic hazard (H410)
  • 'DANGER' signal word — highest hazard classification

Safety Score

18

Avoid

Based on EU regulatory data, published safety research, and ingredient function analysis.

References

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EU CosIng Database

European Commission cosmetic ingredient registry

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This information is for educational purposes only and does not constitute medical advice. Always consult a healthcare professional for skin concerns or allergies.