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Banned antimicrobial

2,2'-Dihydroxy-3,3',5,5',6,6'-hexachlorodiphenylmethane (Hexachlorophene (INN))

CAS 70-30-4
6

Safety score · 0–100

Avoid

Derived from EU CosIng regulatory status, PubChem hazard data and published research. How we score.

A chlorinated antimicrobial that caused infant neurotoxicity tragedies and is now prohibited from general cosmetic use under EU rules. It is also a globally regulated persistent organic pollutant.

Skin benefits

  • Historically used as a strong antibacterial agent
  • Limited authorised use as a preservative under strict EU conditions

Known concerns

  • Listed in EU Cosmetic Regulation Annex II as prohibited in most cosmetic products
  • Neurotoxic, with historical infant fatalities from talc contamination
  • Persistent organic pollutant under the Stockholm Convention
  • Bioaccumulative chlorinated phenol with developmental toxicity

References

EU

EU CosIng database

European Commission cosmetic ingredient registry: regulatory status, restrictions, authorised functions.

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This profile is for educational purposes and does not constitute medical advice. Regulatory status and scientific understanding evolve, so always read the physical product label and consult a healthcare professional for personal concerns.