Skip to content

Other

2,2'-[(4-Amino-3-nitrophenyl)imino]bisethanol hydrochloride and its salts

CAS 29705-39-3 - 94158-13-1
38

Safety score · 0–100

Caution

Derived from EU CosIng regulatory status, PubChem hazard data and published research. How we score.

A nitro-substituted phenylenediamine hair dye intermediate with sensitisation concerns, permitted at up to 2.5% (as hydrochloride) but requiring oxidative conditions for safe use.

This compound is a nitro-substituted m-phenylenediamine derivative used as a hair dye intermediate in oxidative colouring systems. The nitro group on the aromatic ring (para to the imino-bisethanol substituent) contributes to high tinctorial power but also raises sensitisation and potential genotoxicity concern, as nitro groups on aromatic amines can undergo metabolic reduction to reactive nitrenium ions. A maximum concentration of 2.5% (expressed as the hydrochloride salt) applies under EU Annex III, with use restricted to oxidative hair dye applications only.

Known concerns

  • Skin sensitisation potential
  • Potential genotoxicity from metabolic activation of nitro group
  • Aryl amine metabolite concern

References

EU

EU CosIng database

European Commission cosmetic ingredient registry: regulatory status, restrictions, authorised functions.

Related others

38
2,3-Dichloro-2-methylbutane
Other
 38
2-HEXYLOXY-P-PHENYLENEDIAMINE HCL
Other
 38
2-T-BUTYLCYCLOHEXYL ACETATE
Other
 38
2-[(3-Amino-4-methoxyphenyl)amino]ethanol and its sulphate
Other
 38
3-Amino-7- (dimethylamino)-2- methoxyphenoxazin- 5-ium chloride
Other
 38
4-NITRO-O-PHENYLENEDIAMINE DIHYDROCHLORIDE
Other
 38
4-[(2-Nitrophenyl)amino]phenol
Other
 38
5-Chloro-2-(2,4-dichlorophenoxy)phenol
Other

Check your shelf

Find 2,2'-[(4-Amino-3-nitrophenyl)imino]bisethanol hydrochloride and its salts in your products.

Scan any cosmetic product with LuxSense to see if it contains 2,2'-[(4-Amino-3-nitrophenyl)imino]bisethanol hydrochloride and its salts and get a full ingredient breakdown with safety scores.

This profile is for educational purposes and does not constitute medical advice. Regulatory status and scientific understanding evolve, so always read the physical product label and consult a healthcare professional for personal concerns.