1,3-BIS-(2,4-DIAMINOPHENOXY) PROPANE HCL
Other
Caution
CAS Number: 74918-21-1
About 1,3-BIS-(2,4-DIAMINOPHENOXY) PROPANE HCL
A polyaminophenoxy hair dye intermediate with documented sensitization risk and EU regulatory restrictions under Annex III.
Detailed Analysis
1,3-Bis-(2,4-Diaminophenoxy) Propane HCl is listed in EU Annex III/202, restricting its use as a hair colorant. As a primary aromatic amine derivative, it functions as a coupler in oxidative hair dye systems. The dihydrochloride salt improves water solubility but also increases potential for skin absorption. It is a documented contact allergen and is restricted to professional use only in several jurisdictions. Positive patch test rates in dermatitis patients indicate moderate sensitization potential.
What It Does
Known Concerns
- ⚠ EU Annex III restriction (III/202)
- ⚠ Documented contact allergen
- ⚠ Primary aromatic amine - theoretical carcinogen concern under metabolic activation
- ⚠ Professional use only in some markets
Safety Score
Caution
Based on EU regulatory data, published safety research, and ingredient function analysis.
References
EU CosIng Database
European Commission cosmetic ingredient registry
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Download LuxSenseThis information is for educational purposes only and does not constitute medical advice. Always consult a healthcare professional for skin concerns or allergies.